Politico has a headline that is rather striking, but the emphasis is probably not wholly wrong. One of the warning signs that Eric Blair and I used to talk about, years back, was the states organizing in defiance of the Federal government. The refusal to abide by orders here has been licensed by SCOTUS, in the recent Roberts decision.
For now, then, the refusal is entirely legal, and does not represent a crisis -- just a defiance. The use of state governments to openly oppose the Federal, though, is something that bears watching. State governments are quite powerful even individually when compared to protest movements or political rallies.